[A15897] CAS 94594-90-8 | (1S,2R)-(-)-10,2-Camphorsultam, 99% | Alfa
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Brand: Alfa Aesar
94594-90-8 | C10H17NO2S | 10,10-dimethyl-4λ⁶-thia-3-azatricyclo[5.2.1.0²,⁶]decane-4,4-dione
Chemical Identifiers
CAS
94594-90-8
Molecular Weight (g/mol)
215.31
Synonym
10,10-dimethyl-4λ⁶-thia-3-azatricyclo[5.2.1.0²,⁶]decane-4,4-dione
SMILES
CC1(C)C2CCC1C1NS(=O)(=O)CC21
InChI Key
IHFYOCYXHWUKQJ-UHFFFAOYNA-N
Molecular Formula
C10H17NO2S
IUPAC Name
10,10-dimethyl-4λ⁶-thia-3-azatricyclo[5.2.1.0²,⁶]decane-4,4-dione
Specifications
Form
Crystals or powder or crystalline powder
Assay (GC)
≥98.5%
Optical Rotation
-33 ± 1° (c=1 in ethanol)
Appearance (Color)
White to pale cream
Melting Point (clear melt)
180.0-188.0°C
설명
(1S,2R)-(-)-10,2-Camphorsultam is used in the asymmetric synthesis of (S)- and (R)-N-Fmoc-S-trityl-α-methylcysteine. It is used as proton source in the synthesis of chiral α,γ-substituted γ-butyrolactones. It is also employed as a chiral probe for the optical resolution by HPLC and X-ray crystallographic determination of the absolute stereochemistry of carboxylic acids. Also used to prepare N-acryloyl derivatives which are employed as dienophiles in asymmetric Diels-Alder reactions. and for other asymmetric transformations.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
(1S,2R)-(-)-10,2-Camphorsultam is used in the asymmetric synthesis of (S)- and (R)-N-Fmoc-S-trityl-α-methylcysteine. It is used as proton source in the synthesis of chiral α,γ-substituted γ-butyrolactones. It is also employed as a chiral probe for the optical resolution by HPLC and X-ray crystallographic determination of the absolute stereochemistry of carboxylic acids. Also used to prepare N-acryloyl derivatives which are employed as dienophiles in asymmetric Diels-Alder reactions. and for other asymmetric transformations.
(1S,2R)-(-)-10,2-Camphorsultam is used in the asymmetric synthesis of (S)- and (R)-N-Fmoc-S-trityl-α-methylcysteine. It is used as proton source in the synthesis of chiral α,γ-substituted γ-butyrolactones. It is also employed as a chiral probe for the optical resolution by HPLC and X-ray crystallographic determination of the absolute stereochemistry of carboxylic acids. Also used to prepare N-acryloyl derivatives which are employed as dienophiles in asymmetric Diels-Alder reactions. and for other asymmetric transformations.
Solubility
Slightly soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents.
Other References:
Beilstein:83811
GHS Hazard and Precautionary Statements
Hazard Statements:H315-H319-H335
GHS H StatementH315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Risk & Safety
TSCA:No
경고:RUO – Research Use Only
CAS94594-90-8FORMULAC10H17NO2SMDLMFCD00066271
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
