[A15922] CAS 128-08-5 | N-Bromosuccinimide, 99% | Alfa

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Brand: Alfa Aesar

128-08-5 | C4H4BrNO2 | N-bromosuccinimide N-bromosuccimide NBS succinbromide succinibromimide succinbromimide

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Chemical Identifiers

CAS
128-08-5
Molecular Weight (g/mol)
177.99
Synonym
N-bromosuccinimide N-bromosuccimide NBS succinbromide succinibromimide succinbromimide
SMILES
BrN1C(=O)CCC1=O
InChI Key
PCLIMKBDDGJMGD-UHFFFAOYSA-N
Molecular Formula
C4H4BrNO2
IUPAC Name
1-bromopyrrolidine-2,5-dione

Specifications

Appearance (Color)
White to cream or pale yellow
Form
Powder or crystalline powder
Assay (Iodometric Titration)
≥98.5 to ≤101.5%
Identification (FTIR)
Conforms
Melting Point (clear melt)
173.0-182.0?C

설명

N-Bromosuccinimide is a chemical reagent used in electrophilic additions and radical substitution reactions in synthetic organic chemistry. In Wohl-Ziegler reaction, it is involved in allylic and benzylic bromination reaction. It is also used in the alfa-bromination of carbonyl derivatives. In the Hofmann rearrangement, it is used in the presence of a strong base, such as 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) reacts with primary amides to produce a carbamate. It oxidizes silyl ethers to aldehydes in the presence of azobisisobutyronitrile. It is also used for the modification of ribosomal sulfhydryl groups.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Bromosuccinimide is a chemical reagent used in electrophilic additions and radical substitution reactions in synthetic organic chemistry. In Wohl-Ziegler reaction, it is involved in allylic and benzylic bromination reaction. It is also used in the alfa-bromination of carbonyl derivatives. In the Hofmann rearrangement, it is used in the presence of a strong base, such as 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) reacts with primary amides to produce a carbamate. It oxidizes silyl ethers to aldehydes in the presence of azobisisobutyronitrile. It is also used for the modification of ribosomal sulfhydryl groups.

Solubility
Soluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.

Notes
Moisture and light sensitive. Incompatible with strong oxidizing agents, strong acids, strong bases, iron, iron salts, halogenated hydrocarbons, amines and metals. Store in a cool place.

Other References:

Merck Index:14,1438UN Number:UN3261Beilstein:113916

GHS Hazard and Precautionary Statements

Hazard Statements:H272-H290-H315-H317-H319
GHS H StatementH314-H318-H302Causes severe skin burns and eye damage.Causes serious eye damage.Harmful if swallowed.
Precautionary Statements:P210-P220-P221-P234-P261-P264b-P272-P280-P302+P352-P305+P351+P338-P333+P313-P362-P370+P378q-P390-P501c

Risk & Safety

TSCA:Yes

경고:RUO – Research Use Only

CAS128-08-5FORMULAC4H4BrNO2HAZARD CLASS8EINECS204-877-2MDLMFCD00005510PACKAGING GROUPII

Pakage

1000g, 250g, 5000g

brand

Alfa Aesar

SKU: A15922 Category:  Brand:
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[A15922] CAS 128-08-5 | N-Bromosuccinimide, 99% | Alfa

[A15922] CAS 128-08-5 | N-Bromosuccinimide, 99% | Alfa

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