[A15401] CAS 569-58-4 | Aluminon | Alfa
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Brand: Alfa Aesar
569-58-4 | C22H25N3O9 | aurintricarboxylic acid
Chemical Identifiers
CAS
569-58-4
Molecular Weight (g/mol)
475.45
Synonym
aurintricarboxylic acid
SMILES
[NH4+].[NH4+].[NH4+].OC1=CC=C(C=C1C([O-])=O)C(C1C=CC(=O)C(=C1)C([O-])=O)C1=CC=C(O)C(=C1)C([O-])=O
InChI Key
UDPQMNAHKKTHHI-UHFFFAOYNA-N
Molecular Formula
C22H25N3O9
IUPAC Name
triammonium 5-[(3-carboxylato-4-hydroxyphenyl)(3-carboxylato-4-oxocyclohexa-2,5-dien-1-yl)methyl]-2-hydroxybenzoate
Specifications
Sulfated Ash
< 0.2%
Solution Test
1% in water: clear
Appearance (Color)
Dark red
Comment
Suitable forthe determination of aluminium
Form
crystalline powder
설명
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.
Solubility
Soluble in water(800g/L).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Other References:
Merck Index:14,322
GHS Hazard and Precautionary Statements
Hazard Statements:H315-H319
GHS H StatementH315-H319Causes skin irritation.Causes serious eye irritation.
Precautionary Statements:P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
Risk & Safety
TSCA:YesRTECS Number:GU4800000
경고:RUO – Research Use Only
CAS569-58-4FORMULAC22H25N3O9EINECS209-319-1MDLMFCD00040925
| Pakage | 10g, 250g, 50G |
|---|---|
| brand | Alfa Aesar |
