[A14932] CAS 32315-10-9 | Triphosgene, 98% | Alfa
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Brand: Alfa Aesar
32315-10-9 | C3Cl6O3 | triphosgene
Chemical Identifiers
CAS
32315-10-9
Molecular Weight (g/mol)
296.73
Synonym
triphosgene
SMILES
ClC(Cl)(Cl)OC(=O)OC(Cl)(Cl)Cl
InChI Key
UCPYLLCMEDAXFR-UHFFFAOYSA-N
Molecular Formula
C3Cl6O3
IUPAC Name
ditrichloromethyl carbonate
Specifications
Appearance (Color)
Colorless to white to pale cream to pale yellow
Assay (Titration ex Chloride)
≥97.5 to ≤102.5%
Form
Crystals or powder or crystalline powder or lumps or fused solid
Identification (FTIR)
Conforms
설명
Triphosgene is used as a carbonylating agent for aza-peptide synthesis. It reacts with several alfa-amino acids to give the corresponding N-carboxyanhydrides. It is involved in the preparation of the esterification coupling reagent, di-2-thienyl carbonate from 2(5H)-thiophenone. Further, it is used as a reagent in organic synthesis and converts an amino group into isocyanate. In addition to this, it is employed in the preparation of 2-chloronicotinaldehydes through cyclization of the corresponding enamides. It is considered as a useful substitute for phosgene.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Triphosgene is used as a carbonylating agent for aza-peptide synthesis. It reacts with several alfa-amino acids to give the corresponding N-carboxyanhydrides. It is involved in the preparation of the esterification coupling reagent, di-2-thienyl carbonate from 2(5H)-thiophenone. Further, it is used as a reagent in organic synthesis and converts an amino group into isocyanate. In addition to this, it is employed in the preparation of 2-chloronicotinaldehydes through cyclization of the corresponding enamides. It is considered as a useful substitute for phosgene.
Triphosgene is used as a carbonylating agent for aza-peptide synthesis. It reacts with several alfa-amino acids to give the corresponding N-carboxyanhydrides. It is involved in the preparation of the esterification coupling reagent, di-2-thienyl carbonate from 2(5H)-thiophenone. Further, it is used as a reagent in organic synthesis and converts an amino group into isocyanate. In addition to this, it is employed in the preparation of 2-chloronicotinaldehydes through cyclization of the corresponding enamides. It is considered as a useful substitute for phosgene.
Solubility
Soluble in ether, ethanol, tetrahydrofuran, benzene, cyclohexane, chloroform, hexane, carbon tetrachloride, dichloromethane and chlorobenzene. Insoluble in water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with oxidizing agents.
Other References:
UN Number:UN2928Beilstein:1787583
GHS Hazard and Precautionary Statements
Hazard Statements:H314-H330-H335
GHS H StatementH330-H314-H318Fatal if inhaled.Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements:P260-P264b-P271-P280-P284-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Risk & Safety
TSCA:Yes
경고:RUO – Research Use Only
CAS32315-10-9FORMULAC3Cl6O3HAZARD CLASS6.1EINECS250-986-3MDLMFCD00062848PACKAGING GROUPII
| Pakage | 100g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
