[A14165] CAS 10199-89-0 | 4-Chloro-7-nitrobenzofurazan, 98% | Alfa
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Brand: Alfa Aesar
10199-89-0 | C6H2ClN3O3 | 4-chloro-7-nitro-2,1,3-benzoxadiazole
Chemical Identifiers
CAS
10199-89-0
Molecular Weight (g/mol)
199.55
Synonym
4-chloro-7-nitro-2,1,3-benzoxadiazole
SMILES
[O-][N+](=O)C1=CC=C(Cl)C2=NON=C12
InChI Key
IGHBXJSNZCFXNK-UHFFFAOYSA-N
Molecular Formula
C6H2ClN3O3
IUPAC Name
4-chloro-7-nitro-2,1,3-benzoxadiazole
Specifications
Form
Crystals or powder or crystalline powder
Identification (FTIR)
Conforms
Appearance (Color)
Yellow to pale brown
Assay (GC)
≥97.5%
Melting Point (clear melt)
96-101?C
설명
4-Chloro-7-nitrobenzofurazan is used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. It is utilized in the preparation of fluorescent phospholipid-derivative, hydroxynaphthofurazan and 4-chloro-7-nitrobenzofurazan- didecanoylphosphatidylethanolamine. It serves as a fluorescent reagent to label free sulfhydryls and N-terminals within proteins and trapping agent for cysteine sulfenic acid. It is a sensitive chromogenic and fluorogenic reagent. It reacts with trans-1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky’s diene) to prepare regioselectively the silyl enol ether. Further, it is used to label peptides, proteins and other biomolecules. In addition it is used in the synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, functionalized hydroxynaphthofurazan and 7-nitrobenzofurazan (NBD)-labeled maleimide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Chloro-7-nitrobenzofurazan is used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. It is utilized in the preparation of fluorescent phospholipid-derivative, hydroxynaphthofurazan and 4-chloro-7-nitrobenzofurazan- didecanoylphosphatidylethanolamine. It serves as a fluorescent reagent to label free sulfhydryls and N-terminals within proteins and trapping agent for cysteine sulfenic acid. It is a sensitive chromogenic and fluorogenic reagent. It reacts with trans-1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky′s diene) to prepare regioselectively the silyl enol ether. Further, it is used to label peptides, proteins and other biomolecules. In addition it is used in the synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, functionalized hydroxynaphthofurazan and 7-nitrobenzofurazan (NBD)-labeled maleimide.
4-Chloro-7-nitrobenzofurazan is used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. It is utilized in the preparation of fluorescent phospholipid-derivative, hydroxynaphthofurazan and 4-chloro-7-nitrobenzofurazan- didecanoylphosphatidylethanolamine. It serves as a fluorescent reagent to label free sulfhydryls and N-terminals within proteins and trapping agent for cysteine sulfenic acid. It is a sensitive chromogenic and fluorogenic reagent. It reacts with trans-1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky′s diene) to prepare regioselectively the silyl enol ether. Further, it is used to label peptides, proteins and other biomolecules. In addition it is used in the synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, functionalized hydroxynaphthofurazan and 7-nitrobenzofurazan (NBD)-labeled maleimide.
Solubility
Soluble in methanol, dimethylsulfoxide, dimethylformamide and chloroform.
Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
Other References:
Beilstein:614212
GHS Hazard and Precautionary Statements
Hazard Statements:H315-H319
GHS H StatementH315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362
Risk & Safety
TSCA:YesRTECS Number:DF8002400
경고:RUO – Research Use Only
CAS10199-89-0FORMULAC6H2ClN3O3EINECS233-496-4MDLMFCD00005808
| Pakage | 25g, 5g |
|---|---|
| brand | Alfa Aesar |
