[A10837] CAS 109-01-3 | 1-Methylpiperazine, 98+% | Alfa
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Brand: Alfa Aesar
109-01-3 | C5H12N2 | piperazine, 1-methyl-
Chemical Identifiers
CAS
109-01-3
Molecular Weight (g/mol)
100.17
Synonym
piperazine, 1-methyl-
SMILES
CN1CCNCC1
InChI Key
PVOAHINGSUIXLS-UHFFFAOYSA-N
Molecular Formula
C5H12N2
IUPAC Name
1-methylpiperazine
Specifications
Form
Liquid
Assay (GC)
≥98.0%
Identification (FTIR)
Conforms
Refractive Index
1.4635-1.4675 @ 20?C
Appearance (Color)
Clear colorless to pale yellow
설명
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.
Solubility
Miscible with water and methanol.
Notes
Hygroscopic. Moisture sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.
Other References:
UN Number:UN2734Beilstein:102724
GHS Hazard and Precautionary Statements
Hazard Statements:H226-H302+H312+H332-H314-H317-H335
GHS H StatementH331-H314-H318-H226-H302-H312 Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor. Harmful if swallowed. Harmful in contact with skin.
Precautionary Statements:P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c
Risk & Safety
TSCA:YesRTECS Number:TM1225000
경고:RUO – Research Use Only
CAS109-01-3FORMULAC5H12N2HAZARD CLASS8EINECS203-639-5MDLMFCD00005966PACKAGING GROUPII
| Pakage | 100ml, 2500ml, 500ml |
|---|---|
| brand | Alfa Aesar |
