[A10720] CAS 6148-64-7 | Ethyl potassium malonate, 98% | Alfa

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Brand: Alfa Aesar

6148-64-7 | C5H8KO4 | ethyl hydrogen malonate potassium

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Chemical Identifiers

CAS
6148-64-7
Molecular Weight (g/mol)
171.21
Synonym
ethyl hydrogen malonate potassium
SMILES
[K].CCOC(=O)CC(O)=O
InChI Key
HRBCMCJOBRIIQG-UHFFFAOYSA-N
Molecular Formula
C5H8KO4
IUPAC Name
3-ethoxy-3-oxopropanoic acid potassium

Specifications

Appearance (Color)
White to cream
Form
Crystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)
≥97.5 to ≤102.5%

설명

Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig’s base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig′s base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Other References:

Beilstein:3721682

GHS Hazard and Precautionary Statements

Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Risk & Safety

TSCA:No

경고:RUO – Research Use Only

CAS6148-64-7FORMULAC5H8KO4EINECS228-156-7MDLMFCD00035603

Pakage

100g, 25g, 500g

brand

Alfa Aesar

SKU: A10720 Category:  Brand:
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[A10720] CAS 6148-64-7 | Ethyl potassium malonate, 98% | Alfa

[A10720] CAS 6148-64-7 | Ethyl potassium malonate, 98% | Alfa

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