[A10315] CAS 623-33-6 | Glycine ethyl ester hydrochloride, 99% | Alfa
0 ₩
family_key 없음
Brand: Alfa Aesar
623-33-6 | C4H10ClNO2 | glycine, ethyl ester, hydrochloride
Chemical Identifiers
CAS
623-33-6
Molecular Weight (g/mol)
139.58
Synonym
glycine, ethyl ester, hydrochloride
SMILES
[Cl-].CCOC(=O)C[NH3+]
InChI Key
TXTWXQXDMWILOF-UHFFFAOYSA-N
Molecular Formula
C4H10ClNO2
IUPAC Name
2-ethoxy-2-oxoethan-1-aminium chloride
Specifications
Form
Crystals or powder or crystalline powder
Identification (FTIR)
Conforms
Melting Point (clear melt)
142.0-149.0°C
Appearance (Color)
White
Assay (Titration ex Chloride)
≥98.5 to ≤101.5%
설명
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
Solubility
Soluble in water (>1000 mg/ml at 20°C), ethanol, DMSO, and methanol.
Notes
Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.
Other References:
Beilstein:3594034
GHS Hazard and Precautionary Statements
Hazard Statements:Danger
GHS H StatementH318 Causes serious eye damage.
Precautionary Statements:GHS P Statement
P280-P305+P351+P338-P310
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
P280-P305+P351+P338-P310
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
Risk & Safety
TSCA:YesRTECS Number:MC0525000
경고:RUO – Research Use Only
CAS623-33-6FORMULAC4H10ClNO2EINECS210-787-4MDLMFCD00012871
| Pakage | 100g, 2500g, 500g |
|---|---|
| brand | Alfa Aesar |
