[16568] DL-1,4-Dithiothreitol, 99%, for biochemistry | Acros
0 ₩
Brand: Acros Organics
| C4H10O2S2 | L-dithiothreitol cleland reagent sputolysin meso-2,3-butanediol L-dtt clelands reagent reagent, cleland 2.3-butylene glycol (R,R)-2,3-butylene glycol reagent, cleland’s
Chemical Identifiers
CAS
3483-12-3
Molecular Weight (g/mol)
154.24
Synonym
L-dithiothreitol cleland reagent sputolysin meso-2,3-butanediol L-dtt clelands reagent reagent, cleland 2.3-butylene glycol (R,R)-2,3-butylene glycol reagent, cleland’s
SMILES
O[C@@H](CS)[C@@H](O)CS
InChI Key
VHJLVAABSRFDPM-IMJSIDKUSA-N
Molecular Formula
C4H10O2S2
IUPAC Name
(2R,3R)-1,4-disulfanylbutane-2,3-diol
Specifications
Melting point
38°C to 43°C
Appearance (Color)
White
Appearance (Form)
Powder or beads
Infrared spectrum
Conforms
Titration Iodimetric
98.5 to 101.5 %
설명
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
- 1,4-Dithiothreitol (DTT or Cleland’s reagent) reduces disulfide bonds in proteins, leading to loss of native conformation
- DTT is not stable in solution and should be prepared in small aliquots prior to use; the use of EDTA in the solution can increase the half-life of DTT
- Typically used at a final concentration of 0.1M for protein stabilization; recommended to create a 1M stock
Applications
- Protects thiol groups from oxidation and acts as a chemical chelator in solution; maintains proteins in the denatured state
- Common applications include SDS-page electrophoresis and protein isolation
Other References:
Merck Index:15, 3419Beilstein:01, III, 2360
GHS Hazard and Precautionary Statements
Hazard Statements:Serious eye damage/eye irritation (category 2), Acute toxicity (category 4), Specific target organ toxicity after single exposure (category 3), Skin corrosion/irritation (category 2)
Causes serious eye irritation, Harmful if swallowed, May cause respiratory irritation, May form combustible dust concentrations in air, Causes skin irritation
Risk & Safety
경고:RUO – Research Use Only
CAS3483-12-3FORMULAC4H10O2S2MDLMFCD00004877PACKAGING GROUPIII
| Pakage | 100g, 1g, 25g, 5g, 500g |
|---|---|
| brand | Acros Organics |
