[32842] CAS 33069-62-4 | Paclitaxel, 99+% | Acros
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Brand: Acros Organics
33069-62-4 | C47H51NO14 | paclitaxel
Chemical Identifiers
CAS
33069-62-4
Molecular Weight (g/mol)
853.92
Synonym
paclitaxel
SMILES
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
InChI Key
RCINICONZNJXQF-VAZQATRQSA-N
Molecular Formula
C47H51NO14
IUPAC Name
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
Specifications
Appearance (Color)
White
Appearance (Form)
Powder
Infrared spectrum
Conforms
Melting point
203°C to 223°C
HPLC
>=99.0 %
설명
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Paclitaxel is a naturally ocurring compound originally isolated from the tree T. brevifolia
Paclitaxel binds tubulin and stabilizes microtubule formation, preventing disassembly
Paclitaxel is used as a drug to arrest cells at the mitotic checkpoint and block cell cycle progression, thus inducing death of cancer cells
Applications
Paclitaxel can be used in preclinical laboratory research on diseases such as cancer, heart disease, inflammatory disorders, and hepatic fibrosis
Paclitaxel can be used as a tool in cell biology to study mitotic checkpoint arrest conditions and downstream signaling cascades
Other References:
Merck Index:15, 7081
GHS Hazard and Precautionary Statements
Hazard Statements:GHS Signal Word: Danger
GHS H Statement: Causes serious eye damage.Suspected of causing cancer.
Precautionary Statements:GHS P Statement:
Wear eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
Use personal protective equipment as required.
Wear eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
Use personal protective equipment as required.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
Risk & Safety
RTECS Number:DA8340700
경고:RUO – Research Use Only
CAS33069-62-4FORMULAC47H51NO14MDLMFCD00869953
| Pakage | 1mg, 25mg, 5mg |
|---|---|
| brand | Acros Organics |
