CAS : 7188-38-7
UN# : UN1992
MDL : MFCD00000002
Hazard Class : 3
EINECS : 230-553-5
Packing Group : II
Chemical Properties
Formula : C5H9N
Formula weight : 83.13
Boiling Point : 90-92° Flash point: -2°(28°F)
Density : 0.735
Refractive Index : 1.3755
Sensitivity : Store at -20°C.
Form : Liquid
Solubility : Soluble in organic solvents such as ethanol, methanol, ether, toluene and dichloromethane.
Literature References
In the presence of a free-radical initiator, can be used in a tin-free procedure for alkyl radical reactions: Angew. Chem. Int. Ed., 43, 3598 (2004). Useful intermediate in multicomponent reactions. For example, forms a reactive 1 : 1 adduct with acetylenic esters, e.g. Dimethyl acetylenedicarboxylate, A11437, which can be trapped with strong C-H acids, such as 4-Hydroxy-6-methyl-2-pyrone, L11457:
Applications
tert-Butyl isocyanide is used in a tin-free procedure for alkyl radical reactions in the presence of a free-radical initiator. It is a useful intermediate in multicomponent reactions. It is also used in the synthesis of coumarines, 4H-chromenes, isoxazolines and to trap 2-cyclopropylidene-1,3-diones.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H225-H330Highly flammable liquid and vapour.Fatal if inhaled.
Precautionary Statements : P210-P303+P361+P353-P304+P340-P320-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Specific treatment is urgent (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 1903156UN#: UN1992
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
