CAS : 5750-76-5
MDL : MFCD03788200
EINECS : 000-000-0
Chemical Properties
Formula : C4HCl3N2
Formula weight : 183.43
Boiling Point : 84°/1mm Flash point: >110°(230°F)
Density : 1.600
Refractive Index : 1.5730
Sensitivity : Ambient temperatures.
Solubility : Not miscible or difficult to mix in water.
Applications
2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. It is also used in the synthesis of EGFR inhibitors.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.Other References : Beilstein: 4449
GHS Hazard and Precautionary Statements
Hazard Statements : H314-H318Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements : P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501aDo not breathe dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 34Causes burns.
안전 문구 : 20-23-26-36/37/39-45When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
