[J67359] CAS 75621-03-3 | CHAPS, Electrophoresis Grade

CAS : 75621-03-3
MDL : MFCD00012116

Other name :

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Chemical Properties

Formula : C32H58N2O7S
Formula weight : 614.88
Melting Point : 156-158°
Sensitivity : Hygroscopic. Store under Nitrogen. Ambient temperatures.
Form : Powder
Solubility : Soluble in water (10 mg/ml). Soluble in DMF and hot methanol.

Applications

CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. It is suitable for isolation of membrane proteins with the following features such as sufficient protein solubilization capability, no denaturing or inactivation of proteins, no interference with protein activities, no precipitation at 4°C, appropriate critical micelle concentrations (CMC) and micelle size, no absorption in the UV region, no toxicity and availability of detergent detection methods.

Grade Specifications

GHS Hazard and Precautionary Statements

Precautionary Statements :
Precautionary Statements :
위험 문구 : 36/37/38Irritating to eyes, respiratory system and skin.
안전 문구 : 26-37-60In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste