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CAS : 53123-88-9
MDL : MFCD00867594
Other name :
SirolimusAY-22989
Chemical Properties
Formula : C51H79NO13
Formula weight : 914.17
Sensitivity : Store at -20°C.
Form : Powder
Solubility : Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.
Applications
Blocks cytokine-mediated signal transduction pathwaysRapamycin is used to inhibit tumor growth by halting tumor cell proliferation and suppressing tumor angiogenesis. It forms a complex with FKBP12 that binds and inhibits the molecular target of rapamycin (mTOR) as well as suppresses the immune system, preventing transplant rejection.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements :
Other References :
Merck : 14,8114
| Pakage | 100mg, 200mg, 50mg |
|---|---|
| brand | Alfa Aesar |
