[J60679] CAS 13957-31-8 | 4-Thiouridine, 98+%

CAS : 13957-31-8
MDL : MFCD00006538
EINECS : 237-735-3

Chemical Properties

Formula : C9H12N2O5S
Formula weight : 260.27
Sensitivity : Store at -20°C.
Form : Crystalline
Solubility : Soluble in water (20 mg/ml), and methanol (10 mg/ml).

Applications

4-Thiouridine is a constituent of several transfer RNA’s. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

GHS Hazard and Precautionary Statements

Hazard Statements :
Precautionary Statements :
위험 문구 :
안전 문구 :
TSCA : 예아니오
RTECS :