[J60681] CAS 31282-04-9 | Hygromycin B

CAS : 31282-04-9
UN# : UN3462
MDL : MFCD06795479
Hazard Class : 6.1
EINECS : 250-545-5
Packing Group : I

Chemical Properties

Formula : C20H37N3O13
Formula weight : 527.53
Sensitivity : Keep Cold.
Form : Lyophilized powder
Solubility : Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.

Applications

An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.Other References :
Merck : 14,4852
UN# : UN3462

GHS Hazard and Precautionary Statements

Hazard Statements : H300-H310-H330-H317-H334-H318Fatal if swallowed.Fatal in contact with skin.Fatal if inhaled.May cause an allergic skin reaction.May cause allergy or asthma symptoms or breathing difficulties if inhaled.Causes serious eye damage.
Precautionary Statements : P260-P301+P310-P304+P340-P305+P351+P338-P320-P330-P361-P405-P501aDo not breathe dust/fume/gas/mist/vapours/spray.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment is urgent (see label).Rinse mouth.Remove/Take off immediately all contaminated clothing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 26/27/28-41-42/43Very toxic by inhalation, in contact with skin and if swallowed.Risk of serious damage to eyes.May cause sensitization by inhalation and skin contact.
안전 문구 : 4-9-20-22-26-27/28-36/37/39-45-60Keep away from living quarters.Keep container in a well-ventilated place.When using do not eat or drink.Do not breathe dust.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.After contact with skin, take off immediately all contaminated clothing, and wash immediately with plenty of … (to be specified by the manufacturer).Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste