CAS : 65-86-1
MDL : MFCD00006027
EINECS : 200-619-8
Other name :
1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acidUracil-4-carboxylic acid
Chemical Properties
Formula : C5H4N2O4
Formula weight : 156.10
Melting Point : 344-347°
Sensitivity : Ambient temperatures.
Form : Powder
Solubility : Slightly soluble in water.
Applications
Orotic acid is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5?-phospho-α-d-ribose 1?-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5?-monophosphate (OMP). It is used as a starting material for the potential commercial bioproduction of uridine 5?-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. It may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Grade Specifications
GHS Hazard and Precautionary Statements
Precautionary Statements : H302-H315-H319Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.
Precautionary Statements : P280-P305+P351+P338-P302+P352-P321-P362-P501aWear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Take off contaminated clothing and wash before reuse.Dispose of contents/container in accordance with local/regional/national/international regulations.
위험 문구 : 22-36/38Harmful if swallowed.Irritating to eyes and skin.
안전 문구 : 26-36/37In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.
| Pakage | 100g, 500g |
|---|---|
| brand | Alfa Aesar |
