[A15383] CAS 459-57-4 | 4-Fluorobenzaldehyde, 98%

CAS : 459-57-4
UN# : UN3082
MDL : MFCD00003378
Hazard Class : 9
EINECS : 207-293-6
Packing Group : III

Chemical Properties

Formula : C7H5FO
Formula weight : 124.11
Melting Point : -10°
Boiling Point : 180-181° Flash point: 62°(143.6°)(111890°F)
Density : 1.150
Refractive Index : 1.5210
Sensitivity : Air Sensitive. Store under Nitrogen. Ambient temperatures.
Form : Liquid
Solubility : Immiscible with water.

Literature References

For a facile route to 4-aryloxy phenols (Cu catalyzed substitution then Baeyer-Villiger reaction) see: Synthesis, 63 (1991). Ketones behave similarly.

Applications

4-Fluorobenzaldehyde is used in the preparation of pyrazolopyridine derivative, which finds application as mitogen-activated protein kinase (MAPK) inhibitor. It also serves as a synthetic intermediate in the preparation of pharmaceutical compounds.

Grade Specifications

GHS Hazard and Precautionary Statements

Hazard Statements : H315-H319-H335-H227Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.Combustible liquid.
Precautionary Statements : P210-P305+P351+P338-P302+P352-P321-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 385857UN#: UN3082