[A13005] CAS 5331-43-1 | Benzyl carbazate, 98+%

CAS : 5331-43-1
MDL : MFCD00041890
EINECS : 226-230-3

Other name :

Benzyl hydrazinocarboxylateBenzyloxycarbonylhydrazine

Chemical Properties

Formula : C8H10N2O2
Formula weight : 166.18
Melting Point : 66-70°
Sensitivity : Ambient temperatures.
Form : Crystalline
Solubility : Soluble in water (slightly), methanol and DMSO.

Literature References

Reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method: J. Am. Chem. Soc., 74, 470 (1952); 87, 620 (1965); see Appendix 6: Has also been used in a similar manner for the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation; the residual benzyl group is removable by hydrogenolysis: Synthesis, 244 (1980).

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Handle under inert gas. Protect from moisture. Incompatible with strong oxidizing agents.Other References:Beilstein: 1952982

Grade Specifications

Grade Specifications

Hazard Statements : H318-H315-H335Causes serious eye damage.Causes skin irritation.May cause respiratory irritation.
Precautionary Statements : P261-P305+P351+P338-P302+P352-P321-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.