CAS : 616-47-7
UN# : UN2922
MDL : MFCD00005292
Hazard Class : 8
EINECS : 210-484-7
Packing Group : II
Chemical Properties
Formula : C4H6N2
Formula weight : 82.11
Melting Point : -6°
Boiling Point : 195-197° Flash point: 92°(197°F)
Density : 1.031
Refractive Index : 1.4970
Sensitivity : Hygroscopic. Store under Nitrogen. Ambient temperatures.
Form : Liquid
Solubility : Miscible with water.
Literature References
Useful base for peptide coupling, etc. See, e.g.: J. Chem. Soc., Chem. Commun., 2223 (1995). For peptide reagents, see Appendix 6. Undergoes lithiation at the 2-position. Reaction of the Li derivative with ketones followed by dehydration with acetic anhydride is a good route to 2-alkylideneimidazoles: Synthesis, 78 (1990). Likewise, reaction with benzonitrile gives the 2-benzoyl derivative, the carbonyl group of which undergoes Wittig methylenation: Synth. Commun., 20, 321 (1990). Reacts with acid chlorides, including chloroformates, to give N-acylimidazolium salts, which are useful reagents for the acylation of, for example, amino acids: Bull. Soc. Chim. Fr., 1021 (1973).
Applications
1-Methylimidazole is used as a precursor for the synthesis of pyrrole-imidazole polyamides, ionic liquids such as 1-butyl-3-methylimidazolium hexafluorophosphate. It is actively involved in removing acid during the production of diethoxyphenylphosphine. It is used as an intermediate in organic synthesis.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H314-H302-H312-H227Causes severe skin burns and eye damage.Harmful if swallowed.Harmful in contact with skin.Combustible liquid.
Precautionary Statements : P210-P260-P303+P361+P353-P305+P351+P338-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.Do not breathe dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 105197UN#: UN2922
| Pakage | 100g, 2kg, 500g |
|---|---|
| brand | Alfa Aesar |
