[A12461] CAS 7598-61-0 | Diethyl 2,2-diethoxyethylphosphonate, 96%

CAS : 7598-61-0
MDL : MFCD00009236
EINECS : 231-504-0

Other name :

2,2-Diethoxyethylphosphonic acid diethyl esterDiethyl phosphonoacetaldehyde diethyl acetal

Chemical Properties

Formula : C10H23O5P
Formula weight : 254.26
Boiling Point : 101-103°/8mm
Flash point : >110°(230°F)
Density : 1.052
Refractive Index : 1.4278
Sensitivity : Keep Cold. Hygroscopic.
Form : Liquid
Solubility : Soluble in chloroform and dichloromethane. Not miscible or difficult to mix in water.

Literature References

Wadsworth-Emmons olefination with aldehydes leads to ɑß-enals: Bull. Chem. Soc. Jpn., 30, 1498 (1962). This reaction fails for ketones since the ylide loses EtO-. This can be avoided by prior conversion of the acetal to the corresponding cyclohexyl enamine: Org. Synth. Coll., 6, 448 (1988), followed by reaction with the ketone: Org. Synth. Coll., 6, 358 (1988):

Notes

Keep container tightly sealed. It is hygroscopic in nature. It is sensitive to moisture. Store under dry inert gas. Protect from humidity and water.Other References:Beilstein: 1785614

Grade Specifications

Grade Specifications

Hazard Statements : H315-H319Causes skin irritation.Causes serious eye irritation.
Precautionary Statements : P280-P305+P351+P338-P302+P352-P321-P362-P332+P313Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Take off contaminated clothing and wash before reuse.If skin irritation occurs: Get medical advice/attention.