[A11520] CAS 383-63-1 | Ethyl trifluoroacetate, 99%

CAS : 383-63-1
UN# : UN3272
MDL : MFCD00000419
Hazard Class : 3
EINECS : 206-851-6
Packing Group : II

Other name :

Trifluoroacetic acid ethyl ester

Chemical Properties

Formula : C4H5F3O2
Formula weight : 142.08
Melting Point : <-78°
Boiling Point : 60-62°
Flash point : -1°(30°F)
Density : 1.192
Refractive Index : 1.3070
Sensitivity : Moisture Sensitive. Ambient temperatures.
Form : Liquid
Solubility : Slightly miscible with water. Miscible with chloroform and methanol.

Literature References

Reagent for selective trifluoroacetylation of amines. Primary amines can be protected in the presence of secondary, and diamines selectively monoprotected. Primary amines can also be differentiated in terms of steric hindrance: Tetrahedron Lett., 36, 7357 (1995). Esters of perfluoroalkyl carboxylic acids undergo Wittig reactions, for example with the ylide from (3-Phenyl­propyl)­triphenyl­phosphonium bromide, A12669, leading to 1-perfluoroalkyl enol ethers, which are useful precursors of various fluorinated derivatives: J. Org. Chem., 57, 3807 (1992); Org. Synth., 75, 153 (1997):

Notes

Moisture Sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and strong acids.Other References:Beilstein: 1761411UN#: UN3272

Grade Specifications

Grade Specifications

Hazard Statements : H225-H314-H318Highly flammable liquid and vapour.Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements : P210-P241-P303+P361+P353-P305+P351+P338-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.Use explosion-proof electrical/ventilating/lighting/ equipment.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.