[A11235] CAS 4652-27-1 | 4-Methoxy-3-buten-2-one, tech. 90%

CAS : 4652-27-1
MDL : MFCD00008778
EINECS : 225-087-4

Chemical Properties

Formula : C5H8O2
Formula weight : 100.12
Boiling Point : 66-69°/12mm Flash point: 63°(145°F)
Density : 0.990
Refractive Index : 1.4650
Sensitivity : Store at -20°C.
Form : Liquid
Solubility : Miscible with tetrahydrofuran, ether, acetonitrile and benzene.

Literature References

Arylation of the lithio-derivative provides a route to 2-aryl–pyrones: Tetrahedron Lett., 21, 1197, 2773 (1980):

Applications

4-Methoxy-3-buten-2-one is an important precursor for the synthesis of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene and the Danishefsky diene and its equivalent. It is widely used as a reactant in the synthesis of hydroisoquinoline derivatives. It is employed as an intermediate for the synthesis of manzamine.

Grade Specifications

GHS Hazard and Precautionary Statements

Hazard Statements : H227Combustible liquid.
Precautionary Statements : P210-P280-P370+P378a-P403+P235-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.Wear protective gloves/protective clothing/eye protection/face protection.In case of fire: Use for extinction: CO2, powder or water spray.Store in a well-ventilated place. Keep cool.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 1741053