CAS : 535-80-8
MDL : MFCD00002491
EINECS : 208-618-4
Chemical Properties
Formula : C7H5ClO2
Formula weight : 156.57
Melting Point : 154-160°
Boiling Point : 274-276°
Sensitivity : Ambient temperatures.
Form : Crystalline powder
Solubility : Slioghtly soluble in water(0.45 g/L ).
Literature References
The unprotected acid undergoes lithiation at the 2-position with 2.2 moles of s-BuLi in the presence of TMEDA; subsequent reaction with dibromotetrachloroethane provides access to 2-bromo-3-chlorobenzoic acid: Tetrahedron Lett., 36, 881 (1995); Bull. Soc. Chim. Fr., 133, 133 (1996).
Applications
A Pseudomonas species which utilized 3-chlorobenzoic acid as a carbon source converted this compound to 3-hydroxybenzoic and 2, 5-dihydroxybenzoic acids. A methanogenic consortium able to use 3-chlorobenzoic acid as its sole energy and carbon source was enriched from anaerobic sewage sludge. A Pseudomonas putida strain 87 capable of assimilating 3-chlorobenzoic acid as a sole source of carbon and energy (3Cba+) was isolated. coupling of 3-chlorobenzoic acid with phenylboronic acid proceeds at room temperature using 0.5 % Pd and at 100°C using 0.1 % Pd to provide the coupled product in 97 % yeild.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P280g-P305+P351+P338Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Other References:Beilstein: 907218Merck: 14,2123
| Pakage | 100g, 25g, 500g |
|---|---|
| brand | Alfa Aesar |
