[031801] CAS 77-86-1 | Tris(hydroxymethyl)aminomethane, ACS, 99.8-100.1% (Assay, dried basis)

CAS : 77-86-1
MDL : MFCD00004679
EINECS : 201-064-4

Other name :

2-Amino-2-hydroxymethyl-1,3-propanediolTRIS

Chemical Properties

Formula : (HOCH2)3CNH2
Formula weight : 121.14
Melting Point : 171-172°
Boiling Point : 219-220°/10mm
Density : 1.353
Sensitivity : Hygroscopic. Ambient temperatures.
Form : Crystalline
Solubility : Soluble in water, ethylene glycol, methanol, ethanol, dimethyl formamide, acetone, ethyl acetate, olive oil, chloroform and alkaline solution.

Applications

Tris(hydroxymethyl)aminomethane is used as a buffer in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase permeability. As an alternative to sodium bicarbonate, it used in the treatment of metabolic acidosis. It acts as a precursor for the preparation of polymers, oxazolones and oxazolidines.

Grade Specifications

Maximum level of impurities: Absorbance P.T., H2O 2.0%, Insoluble matter 0.005%, Heavy Metals (as Pb) 5ppm, Fe 5ppm

GHS Hazard and Precautionary Statements

Hazard Statements : H315-H319-H335Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P261-P305+P351+P338-P302+P352-P321-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References :

Beilstein : 741883Merck : 14,9772