Chemical Identifiers
CAS
442-51-3
Specifications
Appearance (Color)
White to cream
Assay (HPLC)
≥98.0%
Form
Crystals or powder or crystalline powder
설명
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
Solubility
Soluble in DMSO (100 mM), DMF (∼1.5 mg/ml), ethanol (∼1.5 mg/ml), and PBS (pH 7.2, ∼0.25 mg/ml). Insoluble in water.
Notes
Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
GHS Hazard and Precautionary Statements
Hazard Statements:
Risk & Safety
경고:RUO – Research Use Only
CAS442-51-3EINECS207-131-4PACKAGING GROUPIII
| Pakage | 1g, 250mg |
|---|---|
| brand | Alfa Aesar |
