[L17831] CAS 19493-44-8 | 1-Chloroisoquinoline, 95% | Alfa
0 ₩
Brand: Alfa Aesar
19493-44-8 | C9H6ClN | 1-chloroisoquinoline
Chemical Identifiers
CAS
19493-44-8
Molecular Weight (g/mol)
163.60
Synonym
1-chloroisoquinoline
SMILES
ClC1=C2C=CC=CC2=CC=N1
InChI Key
MSQCQINLJMEVNJ-UHFFFAOYSA-N
Molecular Formula
C9H6ClN
IUPAC Name
1-chloroisoquinoline
Specifications
Melting Point (clear melt)
27.0-39.0?C
Form
Crystals or powder or crystalline powder or fused solid
Appearance (Color)
Pale yellow to yellow to orange to brown
Assay (GC)
≥94.0%
설명
The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.
The product has been used in a Mn-catalyzed cross-coupling with aryl- and alkylmagnesium halides. It has also been used in a Pd-catalyzed cross-coupling with heteroaryl boronic acids and esters. Furthermore, it has been used in a homocoupling reaction to yield bis-isoquinoline, each enantiomer of which might be very useful as a chiral ligand for asymmetric synthesis. 1-Chloroisoquinone is used in the preparation of new aminoisoquinolinylurea derivatives which show antiproliferative activity against melanoma cell lines. It can also be applied to the control of storage age and stability of unstable boronic acids.
Solubility
Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Other References:
Beilstein:2996
GHS Hazard and Precautionary Statements
Hazard Statements:H302+H312-H315-H319-H335
GHS H StatementH315-H319-H335 Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
Risk & Safety
TSCA:No
경고:RUO – Research Use Only
CAS19493-44-8FORMULAC9H6ClNMDLMFCD00024134
| Pakage | 1g, 5g |
|---|---|
| brand | Alfa Aesar |
