[J60823] CAS 7220-79-3 | Methylene Blue trihydrate | Alfa
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Brand: Alfa Aesar
7220-79-3 | C16H24ClN3O3S | 3,7-bis(dimethylamino)-5λ⁴-phenothiazin-5-ylium trihydrate chloride
Chemical Identifiers
CAS
7220-79-3
Molecular Weight (g/mol)
373.90
Synonym
3,7-bis(dimethylamino)-5λ⁴-phenothiazin-5-ylium trihydrate chloride
SMILES
O.O.O.[Cl-].CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C
InChI Key
XQAXGZLFSSPBMK-UHFFFAOYSA-M
Molecular Formula
C16H24ClN3O3S
IUPAC Name
3,7-bis(dimethylamino)-5λ⁴-phenothiazin-5-ylium trihydrate chloride
Specifications
Loss on Drying
8.0 to 18.0%
Assay (unspecified)
0.02% Zinc max.
Assay (unspecified)
98-103%
Assay (unspecified)
0.02% Copper max.
Residue on ignition
1.2% max.
설명
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.
Solubility
Soluble in water, alcohol and chloroform. Insoluble in ether.
Notes
Incompatible with strong oxidizing agents.
Other References:
Merck Index:14,6060Beilstein:3599847
GHS Hazard and Precautionary Statements
Hazard Statements:H302
GHS H StatementH302 Harmful if swallowed.
Precautionary Statements:P264b-P270-P301+P312-P330-P501c
Risk & Safety
TSCA:YesRTECS Number:SP5740000
경고:RUO – Research Use Only
CAS7220-79-3FORMULAC16H24ClN3O3SEINECS200-515-2MDLMFCD00150008
| Pakage | 100g, 250g, 25g |
|---|---|
| brand | Alfa Aesar |
