[J61386] CAS 104594-70-9 | Phenylethyl 3,4-dihydroxycinnamate, 98+% | Alfa
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Brand: Alfa Aesar
104594-70-9 | J61386
Chemical Identifiers
Specifications
Chemical Name or Material
Phenylethyl 3,4-dihydroxycinnamate
CAS
104594-70-9
Melting Point
127°C to 129°C
Color
White to Yellow
Recommended Storage
Store at -20°C
설명
Phenylethyl 3,4-dihydroxycinnamate is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation. It has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. It inhibits HIV-1 integrase and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Phenylethyl 3,4-dihydroxycinnamate is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation. It has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. It inhibits HIV-1 integrase and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity.
Phenylethyl 3,4-dihydroxycinnamate is a potent and specific inhibitor of nuclear transcription factor, NF-κB, activation. It has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. It inhibits HIV-1 integrase and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity.
Solubility
Soluble in ethyl acetate at 50mg/ml. Soluble in DMSO and ethanol.
Notes
Light sensitive. Incompatible with oxidizing agents and heat.
GHS Hazard and Precautionary Statements
Hazard Statements:H315-H319-H335
GHS H StatementH315-H319-H335 Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Risk & Safety
TSCA:NoRTECS Number:UD3334375
경고:RUO – Research Use Only
CAS104594-70-9MDLMFCD00866470
| Pakage | 1g, 250mg |
|---|---|
| brand | Alfa Aesar |
