[J66316] CAS 5505-63-5 | D-Mannosamine hydrochloride, 98% | Alfa
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Brand: Alfa Aesar
5505-63-5 | C6H14ClNO6 | hydrogen D-mannosaminic acid chloride
Chemical Identifiers
CAS
5505-63-5
Molecular Weight (g/mol)
231.63
Synonym
hydrogen D-mannosaminic acid chloride
SMILES
[H+].[Cl-].N[C@@H]([C@@H](O)[C@H](O)[C@H](O)CO)C(O)=O
InChI Key
JMVMHPCPPSZGNY-BZWNWTOPSA-N
Molecular Formula
C6H14ClNO6
IUPAC Name
hydrogen (2S,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanoic acid chloride
Specifications
Appearance (Color)
White to off-white
Assay (HPLC)
97.5% min.
Residue on ignition
0.5% max.
Loss on Drying
0.5% max.
Form
Powder
설명
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer’s patches.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer′s patches.
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer′s patches.
Solubility
Soluble in water and methanol.
Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.
GHS Hazard and Precautionary Statements
Hazard Statements:H302-H315-H317-H319-H335
Precautionary Statements:P261-P264b-P270-P271-P272-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P330-P333+P313-P362-P501c
Risk & Safety
TSCA:Yes
경고:RUO – Research Use Only
CAS5505-63-5FORMULAC6H14ClNO6EINECS226-847-8MDLMFCD00064557
| Pakage | 1g, 500MG |
|---|---|
| brand | Alfa Aesar |
