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[L03801] CAS 50-28-2 | beta-Estradiol, 99% (dry wt.), ca 3% water | Alfa

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Brand: Alfa Aesar

50-28-2 | C18H24O2 | estradiol ovahormon delta-estradiol D-3,17β-estradiol esclim menostar amnestrogen estradurin estrodiolum 雌二醇

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설명

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Chemical Identifiers

CAS
50-28-2
Molecular Weight (g/mol)
272.39
Synonym
estradiol ovahormon delta-estradiol D-3,17β-estradiol esclim menostar amnestrogen estradurin estrodiolum 雌二醇
SMILES
C[C@]12CC[C@H]3[C@@H](CCC4=CC(O)=CC=C34)[C@@H]1CC[C@@H]2O
InChI Key
VOXZDWNPVJITMN-ZBRFXRBCSA-N
Molecular Formula
C18H24O2
IUPAC Name
(1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7-diol

Specifications

Form
Powder
Assay (Silylated GC)
> 98.5%
Water Content (Karl Fischer Titration)
<4.0%
Optical Rotation
+79.0? ? 3.0? (c=1 in Dioxane)
Appearance (Color)
White

설명

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner’s syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner′s syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

Solubility
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.

Notes
Incompatible with strong oxidizing agents.

Other References:

Merck Index:14,3703Beilstein:1914275

GHS Hazard and Precautionary Statements

Hazard Statements:H350-H361fd-H362-H373
GHS H StatementH350-H360 May cause cancer.May damage fertility or the unborn child.
Precautionary Statements:P201-P202-P260-P263-P264b-P270-P271-P281-P304+P340-P308+P313-P501c

Risk & Safety

TSCA:NoRTECS Number:KG2975000

경고:RUO – Research Use Only

CAS50-28-2FORMULAC18H24O2EINECS200-023-8MDLMFCD00003693

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Pakage

1g, 25g, 5g
brand

Alfa Aesar
SKU: L03801 Category:  Brand:
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[L03801] CAS 50-28-2 | beta-Estradiol, 99% (dry wt.), ca 3% water | Alfa

[L03801] CAS 50-28-2 | beta-Estradiol, 99% (dry wt.), ca 3% water | Alfa

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