[L10858] CAS 2373-51-5 | Chloromethyl methyl sulfide, 94% | Alfa

Brand: Alfa Aesar

2373-51-5 | C2H5ClS | chloromethyl methyl sulfide

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Chemical Identifiers

CAS
2373-51-5
Molecular Weight (g/mol)
96.57
MDL Number
MFCD00000923
Synonym
chloromethyl methyl sulfide
SMILES
CSCCl
InChI Key
JWMLCCRPDOIBAV-UHFFFAOYSA-N
Molecular Formula
C2H5ClS
IUPAC Name
chloro(methylsulfanyl)methane

Specifications

Appearance (Color)
Clear colorless to yellow
Assay (GC)
≥92.0%
Form
Liquid

설명

Chloromethyl methyl sulfide is used as a methylene transfer reagent for iron(II) mediated cyclopropanation and for carbonyl and aromatic compounds. It protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.g. with NaH/NaI in DME. It is also used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6 and for reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Chloromethyl methyl sulfide is used as a methylene transfer reagent for iron(II) mediated cyclopropanation and for carbonyl and aromatic compounds. It protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.g. with NaH/NaI in DME. It is also used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6 and for reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent.

Solubility
Soluble in acetonitrile, ether and dichloromethane. Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature: 2 – 8°C. Incompatible with strong oxidizing agents.

Other References:

UN Number:UN1993Beilstein:1730851

GHS Hazard and Precautionary Statements

Hazard Statements:H225-H315-H319-H335
GHS H StatementH225-H315-H319-H335 Highly flammable liquid and vapor.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements:P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c

Risk & Safety

TSCA:NoRTECS Number:WQ3700000

경고:RUO – Research Use Only

CAS2373-51-5FORMULAC2H5ClSHAZARD CLASS3EINECS219-148-4MDLMFCD00000923PACKAGING GROUPII

Pakage

10g, 50G

brand

Alfa Aesar

SKU: L10858 Category:  Brand:
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[L10858] CAS 2373-51-5 | Chloromethyl methyl sulfide, 94% | Alfa

[L10858] CAS 2373-51-5 | Chloromethyl methyl sulfide, 94% | Alfa

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