02100556-CF | CAS 3810-74-0 | Streptomycin sulfate | MPBIO
Key Features and Details
Streptomycin Sulfate
| SKU | 02100556-CF |
| Alternate Names | Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L- lyxofuranosyl- (1->4)- N,N’- bis(aminoiminomethyl)-D-streptamine; Streptomycin A |
| Application Notes | Streptomycin Sulfate is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria. |
| Base Catalog Number | 100556 |
| Beilstein Registry Number | 3894995 |
| Biochemical Physiological Actions | Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
| CAS # | 3810-74-0 |
| EC Number | 223-286-0 |
| Format | Powder |
| Half Life | half-life in plasma is about 2-4 hours |
| Hazard Statements | H302-H361 |
| Molecular Formula | C42H84N14O36S3 |
| Molecular Weight | 1457.376 g/mol |
| Optical Rotation | -77 to -79 ° (c=1% in H2O, 25 °C) (lit.) |
| Personal Protective Equipment | Dust mask, Eyeshields, Faceshields, Gloves |
| RTECS Number | WK4990000 |
| Safety Symbol | GHS07, GHS08 |
| Solubility | greater than or equal to 0.1 mg/mL at 64° F (NTP, 1992) |
| Specific Activity | ≥650 u/mg |
| Typical Working Concentration | Typically used at a concentration of 50-100 mg/liter |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
