02151691-CF | CAS 1115-70-4 | Metformin hydrochloride | MPBIO
Key Features and Details
Metformin Hydrochloride
| SKU | 02151691-CF |
| Alternate Names | N,N-Dimethylimidodicarbonimidic diamine; 1,1-Dimethylbiguanide hydrochloride; DMGG; LA-6023, Metformin |
| Application Notes | 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels. It may be used in the synthesis of the following:• bis(1,1-dimethylbiguanido)copper(II) octahydrate• bis(1,1-dimethylbiguanido)nickel(II)• 1,1-dimethylbiguanidium tetrabromothallate(III) |
| Base Catalog Number | 151691 |
| Biochemical Physiological Actions | Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines. |
| CAS # | 1115-70-4 |
| EC Number | 214-230-6 |
| Format | White Crystalline Powder |
| Hazard Statements | H302-H315-H319 |
| Molecular Formula | C4H12ClN5 |
| Molecular Weight | 165.625 g/mol |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| Purity | ≥98% |
| RTECS Number | DU1800000 |
| Safety Symbol | GHS07 |
| Solubility | In <a class=”pubchem-internal-link CID-962″ href=”https://pubchem.ncbi.nlm.nih.gov/compound/water”>water</a>, 1.06X10+6 mg/L (miscible) at 25 deg C (est) |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| Vapor Pressure | 7.58X10-5 mm Hg at 25 deg C (est) |
