02156738-CF | CAS 10540-29-1 | Tamoxifen | MPBIO
Key Features and Details
Tamoxifen
| SKU | 02156738-CF |
| Alternate Names | [Z]-1-[p-Dimethylaminoethoxyphenyl]-1,2-diphenyl-1-butene; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; ICI 47699; trans-Tamoxifen; Z-Tamoxifen; (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine; trans-1-(p-b- Dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene citrate |
| Application Notes | Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation |
| Base Catalog Number | 156738 |
| Biochemical Physiological Actions | Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. |
| CAS # | 10540-29-1 |
| EC Number | 234-118-0 |
| Hazard Statements | H350-H360-H362 |
| Melting Point | 97 °C |
| Molecular Formula | C26H29NO |
| Molecular Weight | 371.524 g/mol |
| Personal Protective Equipment | Eyeshields, full-face particle respirator, Gloves, respirator cartridge , respirator filter, respirator cartridges |
| pKa | approximately 8.85; approximately 6.9 (in Triton® X-100) |
| RTECS Number | KR5919600 |
| Safety Symbol | GHS08 |
| Solubility | 2.6 [ug/mL] |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| Vapor Pressure | 3.46X10-8 mm Hg at 25 deg C (est) |
