02191158-CF | CAS 9087-70-1 | Aprotinin | MPBIO
Key Features and Details
Aprotinin
| SKU | 02191158-CF |
| Alternate Names | Antagosan; Anikrein; Antilysin(e); Basic pancreatic trypsin inhibitor; BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Trasylol; Triazinin; Zymofren |
| Base Catalog Number | 191158 |
| Biochemical Physiological Actions | Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3. |
| CAS # | 9087-70-1 |
| EC Number | 232-994-9 |
| Extinction Coefficient | E1% (280 nm) = 8.3 (water) |
| Format | Lyophilized powder |
| Isoelectric Point | 10.5 |
| Melting Point | >100 °C |
| Molecular Formula | C284H432N84O79S7 |
| Molecular Weight | 6511.509 g/mol |
| RTECS Number | YN5080000 |
| Source | Bovine Lung |
| Specific Activity | ~4 inhibitor u/mg |
| Sterilization of Solutions | Sterilization of solutions can be done by filtration through a 0.2 um filter. |
| Typical Working Concentration | Equimolar with protease (1-2 ug/ml) |
| Unit Definition | The quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | 277 ± 5 nm (1 max water) |
