02195490-CF | CAS 13292-46-1 | Rifampin, phytopure™ | MPBIO
Key Features and Details
CAS Number: 13292-46-1
| SKU | 02195490-CF |
| Alternate Names | Rifamycin AMP; Rifampicin; 3-(4-Methylpiperazinyliminomethyl)rifamycin SV; Rifampicin |
| Application Notes | Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis. |
| Base Catalog Number | 195490 |
| Beilstein Registry Number | 5723476 |
| Biochemical Physiological Actions | Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. It Inhibits the assembly of DNA and protein into mature virus particles. |
| CAS # | 13292-46-1 |
| EC Number | 236-312-0 |
| Extinction Coefficient | EmM (max absorbance, phosphate buffer,pH 7.38): 33.20 (237 nm); 32.10 (255 nm); 27.00 (334 nm);15.40 (475 nm)(Lit.) |
| Format | Powder |
| Hazard Statements | H302-H315-H319-H335 |
| Isoelectric Point | 4.8(in water)(Lit.) |
| Melting Point | 183 °C |
| Molecular Formula | C43H58N4O12 |
| Molecular Weight | 822.90 |
| Optical Rotation | [α]D25°=+10.6° (c=0.5% in CDCl3)(Lit.) |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| pKa | pKa (in water):1.7 (4-hydroxyl group), 7.9 (4-piperazine nitrogen); in methylcellosolve-water (4:1): 3.6 (4-hydroxyl group), 6.7 (3-piperazine nitrogen)(Lit.) |
| RTECS Number | VJ7000000 |
| Safety Symbol | GHS07 |
| Solubility | <h5 class=”minor-section-title”>Water Solubility</h5>1400 mg/L (at 25 °C) |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | λ max (methanol): 237 – 239, 334 – 338, 475 – 479 nm |
| Vapor Pressure | 3.1X10-34 mm Hg at 25 deg C /Estimated/ |
