[H26425] CAS 548-04-9 | Hypericin, 98% | Alfa

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Brand: Alfa Aesar

548-04-9 | C30H16O8 | 7,11,13,16,18,22-hexahydroxy-5,24-dimethyloctacyclo[13.11.1.1²,¹⁰.0³,⁸.0⁴,²⁵.0¹⁹,²⁷.0²¹,²⁶.0¹⁴,²⁸]octacosa-1(27),2(28),3,5,7,10,12,14,16,18,21,23,25-tridecaene-9,20-dione mono-(123I)iodohypericin hypericin hypericine hypericum red hyperizin (component of) hypericum spp (st. john wort) (component of) hypericum spp (st. john’s wort) hipericina mono-(123i)iodohypericin

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Chemical Identifiers

CAS
548-04-9
Molecular Weight (g/mol)
504.45
Synonym
7,11,13,16,18,22-hexahydroxy-5,24-dimethyloctacyclo[13.11.1.1²,¹⁰.0³,⁸.0⁴,²⁵.0¹⁹,²⁷.0²¹,²⁶.0¹⁴,²⁸]octacosa-1(27),2(28),3,5,7,10,12,14,16,18,21,23,25-tridecaene-9,20-dione mono-(123I)iodohypericin hypericin hypericine hypericum red hyperizin (component of) hypericum spp (st. john wort) (component of) hypericum spp (st. john’s wort) hipericina mono-(123i)iodohypericin
SMILES
CC1=CC(O)=C2C(=O)C3=C(O)C=C(O)C4=C5C(O)=CC(O)=C6C(=O)C7=C(O)C=C(C)C8=C7C(=C56)C(C2=C18)=C34
InChI Key
BTXNYTINYBABQR-UHFFFAOYSA-N
Molecular Formula
C30H16O8
IUPAC Name
7,11,13,16,18,22-hexahydroxy-5,24-dimethyloctacyclo[13.11.1.1²,¹⁰.0³,⁸.0⁴,²⁵.0¹⁹,²⁷.0²¹,²⁶.0¹⁴,²⁸]octacosa-1(27),2(28),3,5,7,10,12,14,16,18,21,23,25-tridecaene-9,20-dione

Specifications

Assay from Supplier’s CofA
≥97.5%
Appearance (Color)
Dark brown to black
Form
Powder

설명

Inhibitor of protein kinase C; induces photosynthesized apoptosisHypercin acts as an antibiotic and antiviral. It is involved in the inhibition of enzyme dopamine beta-hydroxylase action. It also exhibits an anti-HIV and anticancer drug. Further, it is useful in photodynamic therapy. In addition to this, it serves as an inhibitor of protein kinase C which induces photosynthesized apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Hypericin is an anthraquinone derivative found in the yellow flower of Hypericum perforatum (also known as St. John’s wort)
  • This compound has the ability to inhibit protein kinase C, inducing photosynthesized apoptosis

Application

  • It shows antibiotic and antiviral activities
  • The antidepressant activity of this compound could be related to its ability to inhibit the neuronal uptake of serotonin, norepinephrine, dopamine, gamma-aminobutyric acid (GABA), and L-glutamate
  • Since this compound is able to inhibit the assembly and shedding of virus particles in infected cells, hypericin may also prevent the replication of encapsulated viruses
  • It has been described that this compound can also exhibit anti-HIV and anticancer activities
  • Hypericin also displays an effective phototoxic activity and is able to trigger apoptotic pathways, resulting in the formation of reactive oxygen species

Other References:

Merck Index:14,4863Beilstein:1917913

GHS Hazard and Precautionary Statements

Hazard Statements:H302-H317
GHS H StatementH301Toxic if swallowed.
Precautionary Statements:P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c

Risk & Safety

TSCA:NoRTECS Number:SF8472000

경고:RUO – Research Use Only

CAS548-04-9FORMULAC30H16O8EINECS208-941-0MDLMFCD00016683

Pakage

100mg, 25mg

brand

Alfa Aesar

SKU: H26425 Category:  Brand:
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[H26425] CAS 548-04-9 | Hypericin, 98% | Alfa

[H26425] CAS 548-04-9 | Hypericin, 98% | Alfa

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