[A13456] CAS 51-21-8 | 5-Fluorouracil, 99% | Alfa
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Brand: Alfa Aesar
51-21-8 | C4H3FN2O2 | fluorouracil (inn)
Chemical Identifiers
CAS
51-21-8
Molecular Weight (g/mol)
130.08
MDL Number
MFCD00006018
Synonym
fluorouracil|fluorouracil (inn)
SMILES
FC1=CNC(=O)NC1=O
InChI Key
GHASVSINZRGABV-UHFFFAOYSA-N
Molecular Formula
C4H3FN2O2
IUPAC Name
5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
Specifications
Form
Crystalline powder
Appearance (Color)
White to pale cream
Assay from Suppliers CofA
≥98.5%
설명
5-Fluorouracil is used as an antitumor agent in the treatment of anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers. It finds application as a suicide inhibitor due to its irreversible inhibition of thymidylate synthase. It is also used in the treatment of actinic keratoses and bowen’s disease. Further, it serves as a potent antineoplastic agent in clinical use. In addition to this, it acts as a DNA synthesis inhibitor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.
Soluble in dimethylformamide, dimethyl sulfoxide, methanol, hot water, ammonium hydroxide, sodium hydroxide, ethanol and water.
Notes
Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
Other References:
Merck Index:14,4181UN Number:UN2811Beilstein:127172
GHS Hazard and Precautionary Statements
Hazard Statements:H301-H312+H332-H315-H319-H335-H341-H361d
GHS H StatementH360-H341-H373-H302May damage fertility or the unborn child.Suspected of causing genetic defects.May cause damage to organs through prolonged or repeated exposure.Harmful if swallowed.
Precautionary Statements:P201-P202-P261-P264b-P270-P271-P280i-P281-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P362-P501c
Risk & Safety
TSCA:YesRTECS Number:YR0350000
경고:RUO – Research Use Only
CAS51-21-8FORMULAC4H3FN2O2HAZARD CLASS6.1EINECS200-085-6MDLMFCD00006018PACKAGING GROUPIII
| Pakage | 100g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
