[H27260] CAS 59-14-3 | 5-Bromo-2′-deoxyuridine, 99% | Alfa
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Brand: Alfa Aesar
59-14-3 | C9H11BrN2O5 | 5-bdu
Chemical Identifiers
CAS
59-14-3
Molecular Weight (g/mol)
307.10
MDL Number
MFCD00006529
Synonym
bromodeoxyuridine|5-bromodeoxyuridine|BrdU|broxuridine|bromouracil deoxyriboside|5-bromouracil deoxyriboside|5-bromodesoxyuridine|broxuridina|broxuridinum|5-bdu
SMILES
OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(Br)C(=O)NC1=O
InChI Key
WOVKYSAHUYNSMH-RRKCRQDMSA-N
Molecular Formula
C9H11BrN2O5
IUPAC Name
5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Specifications
Appearance (Color)
White to pale cream
Assay (HPLC)
≥98.5%
Optical Rotation
+31.0 ± 1.5? (c=1 in 0.1N NaOH) or +23.0 ± 1? (c=1 in water)
Form
Crystals or powder or crystalline powder
Identification (FTIR)
Conforms (UK sourced product only)
설명
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
5-Bromo-2′-deoxyuridine (BrdU) is a thymidine analog used to label DNA. It is incorporated into newly synthesized DNA in place of thymidine during the S phase of the cell cycle. Cells that were actively proliferating can then be detected by denaturing the DNA and allowing specific antibodies to target the BrdU incorporation. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Solubility
Soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Other References:
Merck Index:14,1452Beilstein:30395
GHS Hazard and Precautionary Statements
Hazard Statements:H315-H319-H335-H341
GHS H StatementH341 Suspected of causing genetic defects.
Precautionary Statements:P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362-P501c
Risk & Safety
TSCA:YesRTECS Number:YU7350000
경고:RUO – Research Use Only
CAS59-14-3FORMULAC9H11BrN2O5EINECS200-415-9MDLMFCD00006529
| Pakage | 1g, 250mg, 5g |
|---|---|
| brand | Alfa Aesar |
