[H26473] CAS 30827-99-7 | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97% | Alfa
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Brand: Alfa Aesar
30827-99-7 | C8H11ClFNO2S | hydrogen aebsf chloride
Chemical Identifiers
CAS
30827-99-7
Molecular Weight (g/mol)
239.69
Synonym
hydrogen aebsf chloride
SMILES
[H+].[Cl-].NCCC1=CC=C(C=C1)S(F)(=O)=O
InChI Key
WRDABNWSWOHGMS-UHFFFAOYSA-N
Molecular Formula
C8H11ClFNO2S
IUPAC Name
hydrogen 4-(2-aminoethyl)benzene-1-sulfonyl fluoride chloride
Specifications
Form
Powder
Melting Point
ca. 180-190?C dec.
Appearance (Color)
White
Proton NMR
To conform to structure
Assay (HPLC)
≥96.0%
설명
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
Solubility
Soluble in water 50 mg/mL or 100% ethanol.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.
Other References:
UN Number:UN3261Beilstein:7604627
GHS Hazard and Precautionary Statements
Hazard Statements:H314-H500
GHS H StatementH314-H318Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements:P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Risk & Safety
TSCA:No
경고:RUO – Research Use Only
CAS30827-99-7FORMULAC8H11ClFNO2SHAZARD CLASS8MDLMFCD00132962PACKAGING GROUPIII
| Pakage | 1g, 250mg |
|---|---|
| brand | Alfa Aesar |
