[B21126] CAS 14430-23-0 | 5,6-Dimethoxyindole, 98% | Alfa

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Brand: Alfa Aesar

14430-23-0 | C10H11NO2 | 5,6-dimethoxy-1H-indole

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Chemical Identifiers

CAS
14430-23-0
Molecular Weight (g/mol)
177.20
Synonym
5,6-dimethoxy-1H-indole
SMILES
COC1=C(OC)C=C2C=CNC2=C1
InChI Key
QODBZRNBPUPLEZ-UHFFFAOYSA-N
Molecular Formula
C10H11NO2
IUPAC Name
5,6-dimethoxy-1H-indole

Specifications

Appearance (Color)
White to pale cream
Melting Point (clear melt)
155.0-161.0?C
Assay (GC)
≥97.5%
Form
Crystals or powder or crystalline powder

설명

It is applied as a reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reaction, in synthesis of benzyl trimethoxyindoles, for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors, for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors and for preparation of tryptophanol derivatives via the Grignard reaction. It is an indole derivative as analgesic anti-inflammatory useful in treatment of pain, inflammation. It is also used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is applied as a reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reaction, in synthesis of benzyl trimethoxyindoles, for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors, for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors and for preparation of tryptophanol derivatives via the Grignard reaction. It is an indole derivative as analgesic anti-inflammatory useful in treatment of pain, inflammation. It is also used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.

Solubility
Insoluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Other References:

Beilstein:5683

GHS Hazard and Precautionary Statements

Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Risk & Safety

TSCA:No

경고:RUO – Research Use Only

CAS14430-23-0FORMULAC10H11NO2EINECS238-402-5MDLMFCD00005675

Pakage

0.25g, 1g

brand

Alfa Aesar

SKU: B21126 Category:  Brand:
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[B21126] CAS 14430-23-0 | 5,6-Dimethoxyindole, 98% | Alfa

[B21126] CAS 14430-23-0 | 5,6-Dimethoxyindole, 98% | Alfa

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