|
SKU |
02193900-CF |
|
Alternate Names |
Insulin sodium salt human; rh-Insulin |
|
Application Notes |
Methods for immobilizing insulin on polystyrene dishes have been reported for applications involving protein-free cell cultures. |
|
Base Catalog Number |
193900 |
|
Biochemical Physiological Actions |
Two-chain polypeptide hormone produced by the ß-cells of pancreatic islets. Its molecular weight is ~5800 Da. The a and ß chains are joined by two interchain disulfide bonds. The a chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. |
|
CAS # |
11061-68-0 |
|
Extinction Coefficient |
EM (278 nm): 6080 (33 mM phosphate, pH 7.0, bovine and porcine) (Lit.) |
|
Format |
Powder |
|
Hazard Statements |
H317 |
|
Isoelectric Point |
~5.3 (for the native protein)(Lit.) |
|
Melting Point |
81 °C |
|
Molecular Formula |
C257H383N65O77S6 |
|
Molecular Weight |
5807.629 g/mol |
|
RTECS Number |
NM8900250 |
|
Specific Activity |
~28 IU/mg |
|
Typical Working Concentration |
1 to 10 ug/mL for cell culture |
|
Unit Definition |
1 unit corresponds to the efficiency of 0.04167 mg international standard substance. An HPLC method exists to test the potency. |
|
Usage Statement |
Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
