[16173] CAS 11018-89-6 | Ouabain octahydrate, 96% | Acros

11018-89-6 | C29H60O20 | 4-[(1R,7S,9R,9bS,10R)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]-dodecahydro-1H-cyclopenta[a]phenanthren-1-yl]-5H-furan-2-one octahydrate

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Chemical Identifiers

CAS
11018-89-6
Molecular Weight (g/mol)
728.78
Synonym
4-[(1R,7S,9R,9bS,10R)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]-dodecahydro-1H-cyclopenta[a]phenanthren-1-yl]-5H-furan-2-one octahydrate
SMILES
O.O.O.O.O.O.O.O.CC1OC(O[C@H]2C[C@@H](O)C3(CO)[C@H]4[C@H](O)CC5(C)[C@H](CCC5(O)C4CCC3(O)C2)C2=CC(=O)OC2)C(O)C(O)C1O
InChI Key
TYBARJRCFHUHSN-HMNHGHQSSA-N
Molecular Formula
C29H60O20
IUPAC Name
4-[(1R,7S,9R,9bS,10R)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one octahydrate

Specifications

Appearance (Color)
White to off-white
Appearance (Form)
Crystalline powder
Infrared spectrum
Conforms
Solubility
(1 % in water) Clear colorless
HPLC
>=95 %

설명

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Ouabain octahydrate is a water-soluble, light-sensitive powder that is stable at ambient temperatures
• It is a glycoside comprised of rhamnose and ouabagenin, and is derived from the ripe seeds of Strophanthus gratus and the bark of Acokanthera ouabaio

Applications

• Ouabain octahydrate works by binding the Na+/K+ ATPase pump, thus disrupting its function, and leading to an increase in intracellular Na+.
• The inhibitory action of ouabain octahydrate on the Na+/K+ pump in cardiac cells makes it a pharmaceutical cardioactive agent
• Ouabain octahydrate has also been found to induce cytotoxic effects through a steroidal signal transduction pathway, in laboratory preparations

Other References:

Merck Index:14, 6901Beilstein:15, V,5, 123

GHS Hazard and Precautionary Statements

Hazard Statements:GHS Signal Word: Danger
GHS H Statement Fatal if swallowed. Toxic if inhaled. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements:GHS P Statement
Wear protective gloves/protective clothing/eye protection/face protection.
Get medical attention/advice if you feel unwell.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Risk & Safety

경고:RUO – Research Use Only

CAS11018-89-6FORMULAC29H60O20MDLMFCD00149240PACKAGING GROUPI

Pakage

1g, 250mg, 25g, 5g

brand

Acros Organics

SKU: 16173 Category:  Brand:
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[16173] CAS 11018-89-6 | Ouabain octahydrate, 96% | Acros

[16173] CAS 11018-89-6 | Ouabain octahydrate, 96% | Acros

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