[21859] CAS 302-95-4 | Deoxycholic acid, sodium salt, 99%, extra pure | Acros
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Brand: Acros Organics
302-95-4 | C24H39NaO4 | sodium 7-deoxycholate
Chemical Identifiers
CAS
302-95-4
Molecular Weight (g/mol)
414.56
MDL Number
MFCD00064139
Synonym
sodium deoxycholate|sodium desoxycholate|deoxycholate sodium|deoxycholic acid sodium salt|desoxycholate sodium|sodium 7-deoxycholate
SMILES
[Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@H](O)CC[C@]12C
InChI Key
FHHPUSMSKHSNKW-SMOYURAASA-M
Molecular Formula
C24H39NaO4
IUPAC Name
sodium (4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoate
Specifications
Appearance (Color)
White to cream
Loss on drying
=<5 % (2 g, 105°C, 4 h)
pH
7.5 to 10 (5 % in water)
Infrared spectrum
Conforms
Heavy metals (as Pb)
=<20 ppm
설명
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- The deoxycholic acid sodium salt is a bile acid choleretic and anionic detergent that allows the solubilization of fats for intestinal absorption
- The compound is an intermediate in the production of corticosteroids
- In animal models it has been shown that this compound can promote tyrosine phosphorylation of β-catenin and its translocation to the nucleus, promoting the activation of β-catenin signaling
Applications
- Deoxycholic acid is mainly useful for the extraction of membrane receptors, other plasma membrane proteins, nuclei isolation, solubilization and isolation of fats, and some components of biological membranes (in an active state)
- It has been used for chemical applications, mainly for the elution or regeneration of specific types of affinity columns. Furthermore, this compound can be used to prevent non-specific binding in affinity chromatography.
- It has been applied in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
- Deoxycholic acid, sodium salt is also recommended for stripping endotoxins
Other References:
Merck Index:14, 2899Beilstein:10, III, 1642
GHS Hazard and Precautionary Statements
Hazard Statements:
GHS H Statement: Harmful if swallowed.May cause respiratory irritation.
Precautionary Statements:GHS P Statement:
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
Risk & Safety
경고:RUO – Research Use Only
CAS302-95-4FORMULAC24H39NaO4MDLMFCD00064139
| Pakage | 100g, 25g, 500g |
|---|---|
| brand | Acros Organics |
