[23030] Dexamethasone, 96% | Acros

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| C22H29FO5 | dexamethasone prednisolon F dexa-cortisyl dexone 1.5 dexone 0.5 dexacidin sunia sol D maxitrol adexone anaflogistico

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Chemical Identifiers

CAS
50-02-2
Molecular Weight (g/mol)
392.47
Synonym
dexamethasone prednisolon F dexa-cortisyl dexone 1.5 dexone 0.5 dexacidin sunia sol D maxitrol adexone anaflogistico
SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI Key
UREBDLICKHMUKA-CXSFZGCWSA-N
Molecular Formula
C22H29FO5
IUPAC Name
(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

Specifications

Appearance (Form)
Crystalline powder
Infrared spectrum
Conforms
UV spectrophotometry
>=95 % (On dried substance)
Appearance (Color)
White to almost white
Specific optical rotation
+86° to +92° (20°C, 589 nm) (c=1, ethanol)

설명

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways

Applications

• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

Other References:

Merck Index:15, 2945

GHS Hazard and Precautionary Statements

Hazard Statements:GHS Signal Word: Warning
GHS H Statement: Suspected of causing cancer.
Precautionary Statements:GHS P Statement:
Use personal protective equipment as required.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

Risk & Safety

경고:RUO – Research Use Only

CAS50-02-2FORMULAC22H29FO5MDLMFCD00064136

Pakage

1g, 250mg, 5g

brand

Acros Organics

SKU: 23030 Category:  Brand:
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[23030] Dexamethasone, 96% | Acros

[23030] Dexamethasone, 96% | Acros

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