CAS : 88-67-5
MDL : MFCD00002419
EINECS : 201-850-7
Chemical Properties
Formula : C7H5IO2
Formula weight : 248.02
Melting Point : 160-164°
Density : 2.250
Sensitivity : Light Sensitive. Ambient temperatures.
Form : Crystalline powder
Solubility : Soluble in dimethyl sulfoxide and methanol
Literature References
Can be used to protect alcohols as their 2-iodobenzoates by DCC coupling. The group is removed by oxidation with chlorine under basic conditions: Tetrahedron Lett., 28, 5005 (1987). In the presence of Tetrakis(triphenylphosphine)palladium(0), 10548, and zinc chloride, undergoes cyclization with terminal acetylenes to give isocoumarins: J. Org. Chem., 60, 3711 (1995): For related reactions, see 4,4-Dimethyl-2-pentyne, L10210, 2-Iodoaniline, A13059 and 2-Iodophenol, A13599.
Applications
Reagent for detection of sulfhydryl groups in proteins2-Iodobenzoic acid acts as a precursor in the preparation of 2-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane, which finds application as an oxidizing agent in synthetic chemistry. It is also used in Suzuki reaction.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H302-H315-H319-H335Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P261-P305+P351+P338-P302+P352-P321-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 1861406Merck: 14,5030
| Pakage | 100g, 25g, 500g |
|---|---|
| brand | Alfa Aesar |
