[A10831] CAS 127-07-1 | Hydroxyurea, 98% | Alfa
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Brand: Alfa Aesar
127-07-1 | CH4N2O2 | hydroxyurea hydroxicarbamidum carbamohydroximic acid hydroxycarbamine ureaphil hydroxyurea (substance) hydroxycarbamid hydreia hydura hydrea
Chemical Identifiers
CAS
127-07-1
Molecular Weight (g/mol)
76.06
Synonym
hydroxyurea hydroxicarbamidum carbamohydroximic acid hydroxycarbamine ureaphil hydroxyurea (substance) hydroxycarbamid hydreia hydura hydrea
SMILES
NC(=O)NO
InChI Key
VSNHCAURESNICA-UHFFFAOYSA-N
Molecular Formula
CH4N2O2
IUPAC Name
hydroxyurea
Specifications
Appearance (Color)
White to cream or yellow
Assay (HPLC)
≥97.5%
Identification (FTIR)
Conforms
Proton NMR
Conforms to structure (non-U.S. specification)
Form
Crystals or powder or crystalline powder
설명
Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Soluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Notes
Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Other References:
Merck Index:14,4848Beilstein:1741548
GHS Hazard and Precautionary Statements
Hazard Statements:H340-H360D
GHS H StatementH340-H360;May cause genetic defects.May damage fertility or the unborn child.
Precautionary Statements:P201-P202-P281-P308+P313-P501c
Risk & Safety
TSCA:NoRTECS Number:YT4900000
경고:RUO – Research Use Only
CAS127-07-1FORMULACH4N2O2EINECS204-821-7MDLMFCD00007943
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
