CAS : 372-48-5
UN# : UN1993
MDL : MFCD00006224
Hazard Class : 3
EINECS : 206-757-5
Packing Group : III
Chemical Properties
Formula : C5H4FN
Formula weight : 97.09
Boiling Point : 124-126° Flash point: 24°(75°F)
Density : 1.129
Refractive Index : 1.4670
Sensitivity : Ambient temperatures.
Form : Liquid
Solubility : Soluble in water.
Literature References
The possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine makes 2-fluoropyridine a useful precursor of a wide range of 2,3-disubstituted pyridines. See, e.g.: J. Org. Chem., 53, 2740 (1988):
Applications
2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements : H226-H315-H319-H335Flammable liquid and vapour.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P210-P241-P303+P361+P353-P305+P351+P338-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.Use explosion-proof electrical/ventilating/lighting/ equipment.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.Other References:Beilstein: 1515UN#: UN1993
| Pakage | 100g, 10g, 250g, 25g |
|---|---|
| brand | Alfa Aesar |
