[A12197] CAS 6112-76-1 | 6-Mercaptopurine monohydrate, 98% | Alfa
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Brand: Alfa Aesar
6112-76-1 | C5H6N4OS | mercaptopurine hydrate
Chemical Identifiers
CAS
6112-76-1
Molecular Weight (g/mol)
170.19
Synonym
mercaptopurine hydrate
SMILES
O.S=C1N=CNC2=C1NC=N2
InChI Key
WFFQYWAAEWLHJC-UHFFFAOYSA-N
Molecular Formula
C5H6N4OS
IUPAC Name
6,7-dihydro-3H-purine-6-thione hydrate
Specifications
Appearance (Color)
Yellow
Assay (HPLC)
≥97.5%
Loss on Drying
5.59-15.08% (200?C/constant weight) (0.5-1.5 waters)
Form
Powder
설명
6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.
Solubility
Soluble in dilute solutions of alkali hydroxides, hot alcohol, and 1 N NaOH (50 mg/ml). Insoluble in water.
Notes
Store in cool, dry place, in well sealed container. Store away from oxidizing agents.
Other References:
Merck Index:14,5871Beilstein:4012091
GHS Hazard and Precautionary Statements
Hazard Statements:H302-H315-H319-H335-H341-H361
GHS H StatementH341-H361-H302 Suspected of causing genetic defects. Suspected of damaging fertility or the unborn child. Harmful if swallowed.
Precautionary Statements:P202-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P362-P501c
Risk & Safety
TSCA:NoRTECS Number:UP0400000
경고:RUO – Research Use Only
CAS6112-76-1FORMULAC5H6N4OSEINECS200-037-4MDLMFCD03854445,MFCD01461928
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
